Chelerythrine chloride, ≥98%, 5 mg

Name: Chelerythrine chloride, ≥98%, 5 mg
SKU: 0215888805

SKU: 0215888805

Synonyms

1,2-Dimethoxy-N-methyl-[1,3]-benzodioxolo[5,6c]phenanthridinium

CAS Number:

3895-92-9

Molecular Formula:

C₂₁H₁₈NO₄Cl

Molecular Weight:

383.8

EC Number:

223-444-9

MDL Number:

MFCD00060717

Packaging size:

5 mg

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Product Description

Chelerythrine is a benzophenanthridine alkaloid.

Application Notes

Chelerythrine Chloride has been shown to inhibit protein kinase C (PKC) by interaction with the PKC catalytic domain. It has also been shown to inhibit PKC translocation from the cytosol to the membrane in isolated ileal synaptosomes.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Inhibits protein kinase C (PKC) by interaction with the PKC catalytic domain | Inhibits PKC translocation from the cytosol to the membrane in isolated ileal synaptosomes

Specifications

SKU	0215888805
Alternate Names	1,2-Dimethoxy-N-methyl-[1,3]-benzodioxolo[5,6c]phenanthridinium
Application Notes	Chelerythrine Chloride has been shown to inhibit protein kinase C (PKC) by interaction with the PKC catalytic domain. It has also been shown to inhibit PKC translocation from the cytosol to the membrane in isolated ileal synaptosomes.
Base Catalog Number	15888805
Biochemical Physiological Actions	Chelerythrine affects translocation of PKC from cytosol to plasma membrane. Shown to prevent neurite growth. Induces apoptosis in a concentration and schedule-dependent manner.
CAS #	3895-92-9
EC Number	223-444-9
Hazard Statements	H302-H312-H315-H319-H332-H335
Melting Point	206 - 208 °C(Lit.)
Molecular Formula	C₂₁H₁₈NO₄Cl
Molecular Weight	383.8
Pack Size	5 mg
Purity	≥98%
RTECS Number	FL9200000
Safety Symbol	GHS07
Solubility	Soluble in water (2 mg/mL), methanol (5 mg/mL - clear yellowish solution) and DMSO (4 mg/mL).
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Documents

Datasheet

DS [02158888]