Vinblastine sulfate

Vinblastine sulfate

Synonyms VLB; Vincaleukoblastine sulfate salt

CAS Number: 143-67-9 Molecular Formula: C46H60N4O13S Molecular Weight: 909.061 g/mol

Beilstein Registry Number: 3659812 EC Number: 205-606-0 MDL Number: MFCD00082457

SKU 02190287-CF
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Description

Product Description

Vinblastine Sulfate

Application Notes

Vinblastine Sulfate is used in cancer research.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used in cancer research

Specifications
SKU 02190287-CF
Alternate Names VLB; Vincaleukoblastine sulfate salt
Application Notes Vinblastine Sulfate is used in cancer research.
Base Catalog Number 190287
Beilstein Registry Number 3659812
Biochemical Physiological Actions Plant alkaloid that inhibits microtubule assembly by binding tubulin and inducing self-association in spiral aggregates in a reaction that appears to be regulated by the C-terminus of β-tubulin and is enhanced by GDP and GTP. Depolymerizes microtubules. Arrests the cell cycle in G2/M-phase by blocking mitotic spindle formation. Triggers Raf-1 activation, phosphorylation of bcl-2-family proteins, induction of p53 expression, and apoptosis in several tumor cell lines. Substrate of Pgp and CYP3A4.
CAS # 143-67-9
EC Number 205-606-0
Format Powder
Hazard Statements H302-H315-H318-H335
Melting Point 543 to 545° F (NTP, 1992)
Molecular Formula C46H60N4O13S
Molecular Weight 909.061 g/mol
RTECS Number YY8400000
Safety Symbol GHS05, GHS07
Solubility greater than or equal to 10 mg/mL at 76.1° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.