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尿嘧啶核苷

尿嘧啶核苷

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CAS:58-96-8 尿苷是核糖核酸(RNA)的四种基本成分之一;其他三种是腺苷、鸟苷和胞苷。在消化含有RNA的食物时,尿苷从RNA中释放出来,并被完整地吸收在肠道中。尿苷在半乳糖的糖酵解途径中发挥作用。

SKU: 02103216-CF

Synonyms
1-B-D-Ribofuranosyluracil; Uracil-1-β-D-ribofuranoside.
CAS Number:
58-96-8
Molecular Formula:
C9H12N2O6
Molecular Weight:
244.2
Beilstein Registry Number:
754902
EC Number:
200-407-5
MDL Number:
MFCD00006526
Product Description

Uridine is one of the four basic components of ribonucleic acid (RNA); the other three are adenosine, guanosine, and cytidine. Upon digestion of foods containing RNA, uridine is released from RNA and is absorbed intact in the gut. Uridine plays a role in the glycolysis pathway of galactose.

Application Notes

Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Metabolic Labelling

Specifications
SKU 02103216-CF
Alternate Names 1-B-D-Ribofuranosyluracil; Uracil-1-β-D-ribofuranoside.
Application Notes Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.
Base Catalog Number 103216
Beilstein Registry Number 754902
CAS # 58-96-8
EC Number 200-407-5
Grade Anhydrous
Melting Point 160 - 171 °C
Molecular Formula C9H12N2O6
Molecular Weight 244.2
Personal Protective Equipment Eyeshields,Faceshields,Gloves,respirator filter
Purity 99%
RTECS Number YR1450000
Solubility Soluble in 0.1 N HCl (50 mg/mL - clear, colorless solution).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (water) 260 - 263 nm
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