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Staurosporine, ≥98%

Staurosporine, ≥98%

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Staurosporine

SKU: 02191400-CF

Synonyms
Staurosporin; Antibiotic AM-2282
CAS Number:
62996-74-1
Molecular Formula:
C28H26N4O3
Molecular Weight:
466.541 g/mol
Beilstein Registry Number:
1060573
MDL Number:
MFCD00077402
Product Description

Staurosporine

Application Notes

Starosporin is use to study the involvement of protein kinases in signal transduction pathways. It arrests normal cells in the G1 checkpoint.Starosporin is used as a potent inhibitor of Protein kinase C and other protein kinases in vitro and in cultured cells, an inducer of apoptosis in many mammalian cell types.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Staurosporine can cross cell membranes in 0.5 to 2.0 hours and has been shown to function in both plant and mammalian systems

Specifications
SKU 02191400-CF
Alternate Names Staurosporin; Antibiotic AM-2282
Application Notes Starosporin is use to study the involvement of protein kinases in signal transduction pathways. It arrests normal cells in the G1 checkpoint.Starosporin is used as a potent inhibitor of Protein kinase C and other protein kinases in vitro and in cultured cells, an inducer of apoptosis in many mammalian cell types.
Base Catalog Number 191400
Beilstein Registry Number 1060573
Biochemical Physiological Actions Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells. Partially reverses MDR, sensitizing cells with MDR phenotype to cytotoxic agents. Inhibits Pgp phosphorylation. However, functional significance of Pgp phosphorylation is ill defined.
CAS # 62996-74-1
Hazard Statements H304-H340-H350
Molecular Formula C28H26N4O3
Molecular Weight 466.541 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type, Gloves, respirator
Purity ≥98%
Safety Symbol GHS08
Source Streptomyces species
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)

Datasheets

Datasheets
English (United States)

Material Safety Data Sheet

Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (Australia)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United States)