Sphingomyelin, 500 mg

Sphingomyelin, 500 mg

Synonyms N-Acyl-4-sphingenyl-1-O-phosphorylcholine; N-Acyl-D-sphingosine-1-phosphocholine

CAS Number: 85187-10-6 Molecular Weight: 764.103 g/mol

EC Number: 286-097-2 MDL Number: MFCD00132361

Packaging size: 500 mg

SKU 0219550690
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Description

Product Description

Sphingomyelin

Application Notes

Sphingomyelin plays a role in signal transduction. It has been observed that sphyngomyelin is a key molecule for ganglioside-bound amyloid β-protein generation on the surface of PC12 cells.Sphingomyelin is suitable for use:• in the preparation of standard during the enzymatic measurement of plasma sphingomyelin levels• to study the binding of Vascular Anticoagulant a (VAC a) to planar phospholipid bilayers• to perform fluorescence polarization of PC16 (N-[a-N-palmitoyl-e-N-(4-nitrobenz-2-oxa-1,3-diazole)-L-lysine]-2-aminoethanol-N- (trimethylaminoethanol) phosphate) in dispersions of co-sonicated lecithin and sphingomyelin• for reconstitution of viral ion channel protein M2 into liposomes• as a standard sample to define spectral fingerproint using Time-of-flight secondary ion mass spectrometry (ToF-SIMS)• to evaluate the contribution of various phospholipids to the formation of foam in the amniotic fluid

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Signal transduction | Used as a key molecule in β-protein generation on the surface of PC12 cells

Specifications
SKU 0219550690
Alternate Names N-Acyl-4-sphingenyl-1-O-phosphorylcholine; N-Acyl-D-sphingosine-1-phosphocholine
Application Notes Sphingomyelin plays a role in signal transduction. It has been observed that sphyngomyelin is a key molecule for ganglioside-bound amyloid β-protein generation on the surface of PC12 cells.Sphingomyelin is suitable for use:• in the preparation of standard during the enzymatic measurement of plasma sphingomyelin levels• to study the binding of Vascular Anticoagulant a (VAC a) to planar phospholipid bilayers• to perform fluorescence polarization of PC16 (N-[a-N-palmitoyl-e-N-(4-nitrobenz-2-oxa-1,3-diazole)-L-lysine]-2-aminoethanol-N- (trimethylaminoethanol) phosphate) in dispersions of co-sonicated lecithin and sphingomyelin• for reconstitution of viral ion channel protein M2 into liposomes• as a standard sample to define spectral fingerproint using Time-of-flight secondary ion mass spectrometry (ToF-SIMS)• to evaluate the contribution of various phospholipids to the formation of foam in the amniotic fluid
Base Catalog Number 19550690
Biochemical Physiological Actions Sphingomyelin is the second most abundant lipid and major sphingolipid component of HDL and the plasma membrane. It forms cholesterol-enriched lipid rafts. It has a key role in the availability of plasma membrane-free cholesterol.
CAS # 85187-10-6
EC Number 286-097-2
Format Powder
Molecular Weight 764.103 g/mol
Pack Size 500 mg
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Purity ~99%
Source Chicken Egg Yolk
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.