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Patulin, 2 mg

Patulin, 2 mg

CN¥0.00

SKU: 0215998902

Synonyms
4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one; claviformin; clavitin; expansin; clavacin; penicidin; mycoin C; mycoin; leucopin; tercinin
CAS Number:
149-29-1
Molecular Formula:
C7H6O4
Molecular Weight:
154.1
Beilstein Registry Number:
149675
EC Number:
205-735-2
MDL Number:
MFCD00005858
Packaging size:
2 mg
Product Description

Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It blocks the farnesylation of proteins in a cell free assay. It inhibits the incorporation of 3H-mevalonate into proteins found in complete cells.

Application Notes

Patulin is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking. It is used to study patulin contamination of bottled wine, DNA-damaging activity of patulin in Escherichia coli., and molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in patulin biosynthesis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic | Inhibitor of potassium uptake | Study of patulin contamination of bottled wine

Specifications
SKU 0215998902
Alternate Names 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one; claviformin; clavitin; expansin; clavacin; penicidin; mycoin C; mycoin; leucopin; tercinin
Application Notes Patulin is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking. It is used to study patulin contamination of bottled wine, DNA-damaging activity of patulin in Escherichia coli., and molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in patulin biosynthesis.
Base Catalog Number 15998902
Beilstein Registry Number 149675
Biochemical Physiological Actions Patulin is genotoxic and may be carcinogenic. It is an inhibitor of potassium uptake and an inducer of ion flux across cell membranes, potentially involving Na<sup>+</sup>-K<sup>+</sup> dependent ATPase. It induces intra- and intermolecular protein crosslinking. CYP619 cytochrome P450s are involved in biosynthesis of patulin in <i>Aspergillus clavatus</i>.
CAS # 149-29-1
EC Number 205-735-2
Extinction Coefficient EM(276 nm) = 14,600 (methanol)(Lit.)
Hazard Statements H300-H315
Melting Point 107 - 110 °C(Lit.)
Molecular Formula C7H6O4
Molecular Weight 154.1
Pack Size 2 mg
Personal Protective Equipment Eyeshields, Gloves
RTECS Number LV2625000
Safety Symbol GHS06
Solubility Soluble in ethyl acetate (5 mg in 0.1 mL), in dichloromethane (10 mg/mL), in water, DMSO(10 mg/mL) and ethanol (25 mg/ mL). Sparingly soluble in ethyl ether or benzene.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)

Datasheets

Datasheets
English (United States)