Orotic acid, potassium salt, 25 g

Orotic acid, potassium salt, 25 g

Synonyms 6-Carboxy-2,4-dihydroxy- pyrimidine; Uracil-6-carboxylic acid

CAS Number: 24598-73-0 Molecular Formula: C5H3KN2O4 Molecular Weight: 194.2

EC Number: 246-341-0 MDL Number: MFCD00039118

Packaging size: 25 g

SKU 0215600025
CN¥0.00
Inquire
Request a quote
Description

Product Description

Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis.

Application Notes

Orotic acid (OA) may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT)

Specifications
SKU 0215600025
Alternate Names 6-Carboxy-2,4-dihydroxy- pyrimidine; Uracil-6-carboxylic acid
Application Notes Orotic acid (OA) may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Base Catalog Number 15600025
CAS # 24598-73-0
EC Number 246-341-0
Molecular Formula C5H3KN2O4
Molecular Weight 194.2
Pack Size 25 g
Personal Protective Equipment Eyeshields, Gloves, respirator filter
RTECS Number RM3201500
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.