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鸟苷-5-三磷酸二钠盐, ≥95%

鸟苷-5-三磷酸二钠盐, ≥95%

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Key features and details

  • Substrate for RNA polymerases and GTPases including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF)

SKU: 02195213-CF

Synonyms
GTP disodium salt; 5′-GTP-Na2
CAS Number:
36051-31-7
Molecular Formula:
C10H14N5O14P3Na2
Molecular Weight:
589.126 g/mol
EC Number:
259-940-7
Product Description

Guanosine-5′-Triphosphate Disodium Salt

Application Notes

Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Substrate for RNA polymerases

Specifications
SKU 02195213-CF
Alternate Names GTP disodium salt; 5′-GTP-Na2
Application Notes Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF).
Base Catalog Number 195213
Biochemical Physiological Actions GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
CAS # 36051-31-7
EC Number 259-940-7
Format Powder
Molecular Formula C10H14N5O14P3Na2
Molecular Weight 589.126 g/mol
Optical Rotation [α]20/D -24±2°, c = 1% in 0.5 M Na2HPO4
Personal Protective Equipment Eyeshields, Faceshields, Gloves, Respirator filter
Purity ≥95%
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (water): 252 ± 3 nm
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