Metronidazole

Metronidazole

Synonyms 2-Methyl-5-nitroimidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(b-Ethylol)-2-methyl-5-nitro-3-azapyrrole

CAS Number: 443-48-1 Molecular Formula: C6H9N3O3 Molecular Weight: 171.156 g/mol

Beilstein Registry Number: 611683 EC Number: 207-136-1 MDL Number: MFCD00009750

SKU 02155710-CF
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Description

Product Description

Metronidazole

Application Notes

Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotics | Chromatography | Antibacterial

Specifications
SKU 02155710-CF
Alternate Names 2-Methyl-5-nitroimidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(b-Ethylol)-2-methyl-5-nitro-3-azapyrrole
Application Notes Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.
Base Catalog Number 155710
Beilstein Registry Number 611683
CAS # 443-48-1
EC Number 207-136-1
Format Powder
Hazard Statements H351
Melting Point 316 to 320° F (NTP, 1992)
Molecular Formula C6H9N3O3
Molecular Weight 171.156 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pH pH of saturated aq soln is 5.8
RTECS Number NI5600000
Safety Symbol GHS08
Solubility >25.7 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 3.1X10-7 mm Hg at 25 deg C (est)