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乙二醇双(2-氨基乙基醚)四乙酸(EGTA)

乙二醇双(2-氨基乙基醚)四乙酸(EGTA)

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Key features and details

CAS:67-42-5 乙二醇双(2-氨基乙基醚)四乙酸(EGTA)

SKU: 02195174-CF

Synonyms
EGTA; GEDTA; O,O'-bis(2-aminoethyl) ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid
CAS Number:
67-42-5
Molecular Formula:
C14H24N2O10
Molecular Weight:
380.35 g/mol
Beilstein Registry Number:
1717370
EC Number:
200-651-2
MDL Number:
MFCD00004291
Product Description

Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid

Application Notes

Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chelating agent

Specifications
SKU 02195174-CF
Alternate Names EGTA; GEDTA; O,O'-bis(2-aminoethyl) ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid
Application Notes Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.
Base Catalog Number 195174
Beilstein Registry Number 1717370
CAS # 67-42-5
EC Number 200-651-2
Format Crystalline
Molecular Formula C14H24N2O10
Molecular Weight 380.35 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pKa < 2, 2.7, 8.8, and 9.5 (Lit.)
Purity ≥98%
RTECS Number AH3760000
Typical Working Concentration as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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