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前列腺素 E2, γ射线照射, ≥99%, 1 mg

前列腺素 E2, γ射线照射, ≥99%, 1 mg

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Key features and details

CAS:363-24-6 地诺前列酮 前列腺素 E2

SKU: 0219457601

Synonyms
[5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2; Dinoprostone
CAS Number:
363-24-6
Molecular Formula:
C20H32O5
Molecular Weight:
352.471 g/mol
Beilstein Registry Number:
4709356
EC Number:
206-656-6
MDL Number:
MFCD00077861
Packaging size:
1 mg
Product Description

Prostaglandin E2

Application Notes

Prostaglandin E2 is use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Study of prostaglandin regulated cell signaling and gene regulation

Specifications
SKU 0219457601
Alternate Names [5Z,11a,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; PGE2; Dinoprostone
Application Notes Prostaglandin E2 is use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.
Base Catalog Number 19457601
Beilstein Registry Number 4709356
Biochemical Physiological Actions Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
CAS # 363-24-6
EC Number 206-656-6
Format Solid
Grade γ-irradiated
Hazard Statements H302-H360
Melting Point 67 °C
Molecular Formula C20H32O5
Molecular Weight 352.471 g/mol
Pack Size 1 mg
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge,respirator filter
Purity ≥99%
RTECS Number UK8000000
Safety Symbol GHS07, GHS08
Solubility Water Solubility58.1 mg/L
Sterility γ-Irradiated
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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