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L-谷氨酸

L-谷氨酸

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Key features and details

CAS:56-86-0 谷氨酸

SKU: 02101793-CF

Synonyms
L-2-Aminopentanedioic acid; (S)-(+)-glutamic acid; L-Glu; Glu; (S)-2-Aminopentanedioic acid; a-aminoglutaric acid; 1-aminopropane-1,3- dicarboxylic acid; Glu; E
CAS Number:
142-47-2
Molecular Formula:
C5H9NO4
Molecular Weight:
169.112 g/mol
Beilstein Registry Number:
1723801
EC Number:
200-293-7
MDL Number:
MFCD00002634
Product Description

L-Glutamic Acid

Application Notes

It is often used as a food additive and flavour enhancer in the form of its salt, known as monosodium glutamate (MSG). A glutamic acid derivative, poly-γ-benzyl-L-glutamate (PBLG), is often used as an alignment medium to control the scale of the dipolar interactions observed. L-Glutamic acid is used in cell culture as a component of MEM non-essential amino acids solution. L-Glutamic acid has been used as a nitrogen source in the culture of Aspergillus fumigatus NRRL 2436 for fumagillin production. The competitive roles of L-glutamic acid and L-aspartic acid in the growth of Oenococcus oeni NCFB 1707 have been studied.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Neuroscience | Neurotransmission

Specifications
SKU 02101793-CF
Alternate Names L-2-Aminopentanedioic acid; (S)-(+)-glutamic acid; L-Glu; Glu; (S)-2-Aminopentanedioic acid; a-aminoglutaric acid; 1-aminopropane-1,3- dicarboxylic acid; Glu; E
Application Notes It is often used as a food additive and flavour enhancer in the form of its salt, known as monosodium glutamate (MSG). A glutamic acid derivative, poly-γ-benzyl-L-glutamate (PBLG), is often used as an alignment medium to control the scale of the dipolar interactions observed. L-Glutamic acid is used in cell culture as a component of MEM non-essential amino acids solution. L-Glutamic acid has been used as a nitrogen source in the culture of Aspergillus fumigatus NRRL 2436 for fumagillin production. The competitive roles of L-glutamic acid and L-aspartic acid in the growth of Oenococcus oeni NCFB 1707 have been studied.
Base Catalog Number 101793
Beilstein Registry Number 1723801
Biochemical Physiological Actions An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). Glutamate is a key compound in cellular metabolism. It is the most abundant excitatory neurotransmitter in the vertebrate nervous system. It also serves as the precursor for the synthesis of the inhibitory GABA in GABA-ergic neurons. This reaction is catalyzed by glutamate decarboxylase (GAD), which is most abundant in the cerebellum and pancreas.
Boiling Point 225 deg C (decomposes)
CAS # 142-47-2
Density 26.2 (saturated <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a> solution at 20 deg C)
EC Number 200-293-7
Format Powder, Free Acid
Isoelectric Point 3.08 (Lit.)
Melting Point 450° F (Decomposes) (NTP, 1992)
Molecular Formula C5H9NO4
Molecular Weight 169.112 g/mol
Optical Rotation +25° to +35° (c=10, 2N HCl )
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pH Between 6,7 and 7,2 (5 % solution)
pKa 2.10 (α-COOH), 9.47 (α-NH2), 4.07 (φ-COOH) (Lit.)
Purity ≥99%
RTECS Number LZ9700000
Solubility greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations