硫酸卡那霉素

硫酸卡那霉素

Synonyms Kanamycin A; Kanamycin sulfate salt

CAS Number: 25389-94-0 Molecular Formula: C18H36N4O11 Molecular Weight: 582.60

EC Number: 246-933-9 MDL Number: MFCD00070253

SKU 02194531-CF
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Description

Product Description

From Streptomyces kanamycetikus. An aminoglycoside bacteriocidal antibiotic that acts against gram-positive and gram-negative bacteria. Inhibits protein biosynthesis by causing a misreading of the 70s-ribosome. Useful in plant cell culture for selection of the kanamycin-resistance gene.

Application Notes

Kanamycin Sulfate used in biotechnology applications to inhibit protein synthesis. Active against many strains of Gram-negative bacteria and Gram positive Staphylococcus aureus and S. epidermis. Some strains of Mycobacterium are sensitive. Most active in alkaline solution. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotics

Specifications
SKU 02194531-CF
Alternate Names Kanamycin A; Kanamycin sulfate salt
Application Notes Kanamycin Sulfate used in biotechnology applications to inhibit protein synthesis. Active against many strains of Gram-negative bacteria and Gram positive Staphylococcus aureus and S. epidermis. Some strains of Mycobacterium are sensitive. Most active in alkaline solution. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene.
Base Catalog Number 194531
Biochemical Physiological Actions Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding.Mode of Resistance:Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.Antimicrobial spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.
CAS # 25389-94-0
EC Number 246-933-9
Format Powder
Grade Cell Culture Grade
Hazard Statements H360
Molecular Formula C18H36N4O11
Molecular Weight 582.60
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Potency ~ 735 ug/mg
RTECS Number NZ3225030
Safety Symbol GHS08
Typical Working Concentration 100 mg/L
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.