Inosine, ≥99%, 5 g

Inosine, ≥99%, 5 g

Synonyms 9-β-D-Ribofuranosylhypoxathine; Hypoxanthine riboside; Hypoxanthosine

CAS Number: 58-63-9 Molecular Formula: C10H12N4O5 Molecular Weight: 268.2

Beilstein Registry Number: 624896 EC Number: 200-390-4 MDL Number: MFCD00066770

Packaging size: 5 g

SKU 0210204905
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Description

Product Description

Inosine is the deaminated form of adenosine. It is a nucleoside consisting of hypoxathine and ribose. Its phosphate ester is inosinic acid. Inosine easily permeates the cell membrane and, taking part in glycolysis and the TCA cycle via the pentose phosphate pathway, elevates the intracellular level of ATP and stimulates biosynthesis of nucleic acids. Adaptation of these metabolic processes activates the cell, and the nucleoside is applicable to various disorders. Inosine accumulates in tissue during periods of ischemia and has been shown to degranulate mast cells in the hamster cheek pouch via activation of an A3 receptor.

Application Notes

Suppresses the increase of glucose and insulin in the blood. Inhibits cytokine production by a posttranscriptional mechanism.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 0210204905
Alternate Names 9-β-D-Ribofuranosylhypoxathine; Hypoxanthine riboside; Hypoxanthosine
Application Notes Suppresses the increase of glucose and insulin in the blood. Inhibits cytokine production by a posttranscriptional mechanism.
Base Catalog Number 10204905
Beilstein Registry Number 624896
Biochemical Physiological Actions Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.
CAS # 58-63-9
EC Number 200-390-4
Melting Point 212-213 °C(dec)
Molecular Formula C10H12N4O5
Molecular Weight 268.2
Pack Size 5 g
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Purity ≥99%
RTECS Number NM7460000
Solubility Soluble in 1 N HCl (30 mg/mL - clear, colorless solution), 50% ammonium hydroxide (10 mg/mL - clear, colorless solution); Slightly soluble in water (1.6 g/100 mL at 20°C); very slightly soluble in ethanol or chloroform; practically insoluble in ether.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance UV/Vis: λ max (water): 248 ± 3nm; OD250/OD260: 1.49 - 1.81; OD280/OD260: 0.21 - 0.31; OD290/OD260: 0.01 - 0.05