Folic acid, >95.0%

Folic acid, >95.0%

Synonyms Pteroylglutamic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid; N-[p-[[(2-amino-4-hydroxy-6-pteridinyl) methyl]amino] benzoyl] glutamic acid; N-(p-[(2-amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl) methylamino] benzoyl) glutamic acid; PGA; Liver Lactobacillus casei factor; Vitamin Bc; Vitamin M; Folsure; PteGlu

CAS Number: 59-30-3 Molecular Formula: C19H19N7O6 Molecular Weight: 441.404 g/mol

Beilstein Registry Number: 100781 EC Number: 200-419-0 MDL Number: MFCD00079305

SKU 02101725-CF
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Description

Product Description

Folic Acid

Application Notes

Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cofactors | Enzymes | Inhibitors and Substrates | Folic Acid Metabolism

Specifications
SKU 02101725-CF
Alternate Names Pteroylglutamic Acid; N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl] amino]benzoyl]-L-glutamic acid; N-[p-[[(2-amino-4-hydroxy-6-pteridinyl) methyl]amino] benzoyl] glutamic acid; N-(p-[(2-amino-4-hydroxypyrimido[4,5-b]pyrazin-6-yl) methylamino] benzoyl) glutamic acid; PGA; Liver Lactobacillus casei factor; Vitamin Bc; Vitamin M; Folsure; PteGlu
Application Notes Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs folate to synthesize DNA, repair DNA, and methylate DNA as well as to act as a cofactor in certain biological reactions. It is especially important in aiding rapid cell division and growth, such as in infancy and pregnancy.
Base Catalog Number 101725
Beilstein Registry Number 100781
Biochemical Physiological Actions Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
CAS # 59-30-3
EC Number 200-419-0
Extinction Coefficient 9.12, 25.1, 26.9 (0.1 M NaOH)(Lit.)
Format Powder
Melting Point 482° F (decomposes) (NTP, 1992)
Molecular Formula C19H19N7O6
Molecular Weight 441.404 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pH A suspension of 1 g of folic acid in 10 ml of <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a> has a pH of 4.0-4.8. Aq solutions prepared with <a class="pubchem-internal-link CID-516892" href="https://pubchem.ncbi.nlm.nih.gov/compound/sodium%20bicarbonate">sodium bicarbonate</a> have a pH between 6.5 and 6.8.
pKa 8.26 (Lit)
Purity >95.0%
RTECS Number LP5425000
Solubility Almost insoluble (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance 256 ± 3 nm (0.1 N NaOH)
Vapor Pressure 6.2X10-20 mm Hg at 25 deg C /Estimated/