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Doxycycline hydrochloride

Doxycycline hydrochloride

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Doxycycline Hydrochloride

SKU: 02195044-CF

Synonyms
Biocamycin; Doxigalumicina; Doxycycline hyclate; Doxy-II; Midoxin; Novadox; Retens; Tetradox; Vibradox; Hydramycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
CAS Number:
10592-13-9
Molecular Formula:
C22H24N2O8 • HCl
Molecular Weight:
480.898 g/mol
Beilstein Registry Number:
5702728
EC Number:
234-198-7
MDL Number:
MFCD07357237
Product Description

Doxycycline Hydrochloride

Application Notes

Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is used to inhibit matrix metalloproteinases and has been used to inhibit the inflammatory response of Lyme Disease.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02195044-CF
Alternate Names Biocamycin; Doxigalumicina; Doxycycline hyclate; Doxy-II; Midoxin; Novadox; Retens; Tetradox; Vibradox; Hydramycin; 2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride
Application Notes Doxycycline hyclate is a synthetic oxytetracycline derivative. It has been used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is used to inhibit matrix metalloproteinases and has been used to inhibit the inflammatory response of Lyme Disease.
Base Catalog Number 195044
Beilstein Registry Number 5702728
Biochemical Physiological Actions Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in studies on wound healing and tissue remodeling.Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is a Broad spectrum antibiotic and bacteriostatic. Doxycycline shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metalloproteinases) in vivo. Doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease acne, rosacea, and rickettsial infections and prophylaxis of anthrax (caused by Bacillus anthracis). It is also effective against Yersinia pestis. Treatment with doxycycline inhibits collagen synthesis.
CAS # 10592-13-9
EC Number 234-198-7
Hazard Statements H302-H315-H319-H335
Molecular Formula C22H24N2O8 • HCl
Molecular Weight 480.898 g/mol
Personal Protective Equipment dust mask , Eyeshields, Gloves
pKa (10 mg/ml)
Potency 43134
Preparation Method P261-P305 + P351 + P338
RTECS Number QI8925000
Source Soluble in water (10 mg/mL - clear; yellowish to yellowish-green solution) and DMSO: soluble (50 mg/mL).
Unit Definition It is typically used at a concentration of 20 ug/mL and is stable in media at 37 °C for approximately 5 days.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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