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Doxorubicin hydrochloride,≥95%

Doxorubicin hydrochloride,≥95%

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Doxorubicin Hydrochloride

SKU: 02159101-CF

Synonyms
Adriamycin; 14-Hydroxydaunomycin; HCl; DOX; Hydroxydaunorubicin hydrochloride; 14-Hydroxydaunomycin hydrochloride; 10-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl) hydrochloride; Doxorubicin
CAS Number:
25316-40-9
Molecular Formula:
C27H29NO11·HCl
Molecular Weight:
579.983 g/mol
Beilstein Registry Number:
4229251
EC Number:
246-818-3
MDL Number:
MFCD00077757
Product Description

Doxorubicin Hydrochloride

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chemotherapeutic agent

Specifications
SKU 02159101-CF
Alternate Names Adriamycin; 14-Hydroxydaunomycin; HCl; DOX; Hydroxydaunorubicin hydrochloride; 14-Hydroxydaunomycin hydrochloride; 10-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl) hydrochloride; Doxorubicin
Base Catalog Number 159101
Beilstein Registry Number 4229251
Biochemical Physiological Actions Doxorubicin hydrochloride blocks RNA polymerase and reverse transcriptase. It also inhibits nucleic acid synthesis and induces apoptosis. Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. The fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
CAS # 25316-40-9
EC Number 246-818-3
Format Powder
Hazard Statements H302-H350
Melting Point 399 to 401° F (Decomposes) (NTP, 1992)
Molecular Formula C27H29NO11·HCl
Molecular Weight 579.983 g/mol
Personal Protective Equipment Eyeshields, Full-face respirator, Gloves, Multi-purpose combination respirator cartridge, Respirator filter
Purity ≥95%
RTECS Number QI9295900
Safety Symbol GHS07, GHS08
Solubility Soluble (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 2.5X10-23 at 25 deg C (est)
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