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Cytosine-β-D-arabinofuranoside hydrochloride

Cytosine-β-D-arabinofuranoside hydrochloride

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Cytosine-Β-D-Arabinofuranoside Hydrochloride

SKU: 02100071-CF

Synonyms
AraC; Arabinosylcytosine; 1-β-D-Arabinofuranosylcytosine; Cytabarine; Cytosine 1-(β-D-Arabino­furanosyl)­cytosine hydrochloride; Ara-C hydrochloride; Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Cytarabine hydrochloride; Cytosine arabinoside hydrochloride; Cylocide; Cytosar Hydrochloride; Iretin; Spongocytidine Hydrochloride
CAS Number:
69-74-9
Molecular Formula:
C9H13N3O5 • HCl
Molecular Weight:
279.677 g/mol
EC Number:
200-713-9
MDL Number:
MFCD00012839
Product Description

Cytosine-Β-D-Arabinofuranoside Hydrochloride

Application Notes

It is used as an antineoplastic and antiviral agent.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Selective inhibitor of DNA synthesis

Specifications
SKU 02100071-CF
Alternate Names AraC; Arabinosylcytosine; 1-β-D-Arabinofuranosylcytosine; Cytabarine; Cytosine 1-(β-D-Arabino­furanosyl)­cytosine hydrochloride; Ara-C hydrochloride; Arabinocytidine hydrochloride; Arabinosylcytosine hydrochloride; Cytarabine hydrochloride; Cytosine arabinoside hydrochloride; Cylocide; Cytosar Hydrochloride; Iretin; Spongocytidine Hydrochloride
Application Notes It is used as an antineoplastic and antiviral agent.
Base Catalog Number 100071
Biochemical Physiological Actions Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway. Does not inhibit RNA synthesis. Anti-leukemia agent.
CAS # 69-74-9
EC Number 200-713-9
Format Powder
Hazard Statements H317-H319-H341-H361
Melting Point 356 to 360° F (NTP, 1992)
Molecular Formula C9H13N3O5 • HCl
Molecular Weight 279.677 g/mol
RTECS Number HA5500000
Safety Symbol GHS07, GHS08
Solubility >42 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λmax (water) 280 ± 6 nm
Vapor Pressure 8.74X10-12 mm Hg at 25 deg C (est)
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