Cytochalasin D

Cytochalasin D

Synonyms Zygosporin A; 3-Benzyl-3,3-alpha, 4, 5, 6, 6-alpha, 9, 10, 12, 15-Decahydro-6, 12, 15-Trihydroxy-4, 10, 12-Trimethyl-5-Methylene-1H-Cycloundec(d)isoindole-1, 11(2H) Dione, 15-Acetate

CAS Number: 22144-77-0 Molecular Formula: C30H37NO6 Molecular Weight: 507.627 g/mol

Beilstein Registry Number: 1632828 EC Number: 244-804-1 MDL Number: MFCD00077706

SKU 02150771-CF
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Description

Product Description

Cytochalasin D

Application Notes

Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Potent inhibitor of actin polymerization

Specifications
SKU 02150771-CF
Alternate Names Zygosporin A; 3-Benzyl-3,3-alpha, 4, 5, 6, 6-alpha, 9, 10, 12, 15-Decahydro-6, 12, 15-Trihydroxy-4, 10, 12-Trimethyl-5-Methylene-1H-Cycloundec(d)isoindole-1, 11(2H) Dione, 15-Acetate
Application Notes Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin.
Base Catalog Number 150771
Beilstein Registry Number 1632828
Biochemical Physiological Actions Disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. Inhibits smooth muscle contraction. Inhibits insulin-stimulated, but not basal, transport of glucose.
CAS # 22144-77-0
EC Number 244-804-1
Format Powder
Hazard Statements H300-H361
Melting Point 491 to 500° F (decomposes) (NTP, 1992)
Molecular Formula C30H37NO6
Molecular Weight 507.627 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
RTECS Number GZ4850000
Safety Symbol GHS06, GHS08
Source Zygosporium mansoni
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.