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Colistin methanesulfonate, 25 mg

Colistin methanesulfonate, 25 mg

CN¥0.00

SKU: 0219415625

Synonyms
Sodium colistinemethanesulfonate; CLM; Colimycin M; Colimycin sodium methanesulfonate; Methanesulfonic acid derivative of Polymyxin E; Polymyxin E sodium methanesulfonate
CAS Number:
8068-28-8
Molecular Formula:
C58H105N16Na5O28S5
EC Number:
232-516-9
MDL Number:
MFCD00130824
Packaging size:
25 mg
Product Description

Methanesulfonic acid derivative of polymyxin E.

Application Notes

Colistin sodium methanesulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination. It is used to study effective treatments of P. aeruginosa infections in cystic fibrosis patients and to study the pharmacokinetics and BAL concentration of colistin in critically ill patients.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 0219415625
Alternate Names Sodium colistinemethanesulfonate; CLM; Colimycin M; Colimycin sodium methanesulfonate; Methanesulfonic acid derivative of Polymyxin E; Polymyxin E sodium methanesulfonate
Application Notes Colistin sodium methanesulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination. It is used to study effective treatments of P. aeruginosa infections in cystic fibrosis patients and to study the pharmacokinetics and BAL concentration of colistin in critically ill patients.
Base Catalog Number 19415625
Biochemical Physiological Actions Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. Cyclopolypeptide antibiotic. Endotoxin-binding capacity Colistin′s activity stems from the hydrophobic and hydrophillic regions. They solubilze the cytoplasmic membrane which contributes to the bactericidal effect .
CAS # 8068-28-8
EC Number 232-516-9
Molecular Formula C58H105N16Na5O28S5
Pack Size 25 mg
Personal Protective Equipment Eyeshields, Gloves, respirator filter
RTECS Number GH1650000
Solubility Soluble in water (200 mg plus 4 mL - clear to very slightly hazy colorless to light yellow solution).
Specific Activity ≥10,000 u/mg
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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Datasheets
English (United States)

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)