Chelerythrine chloride, ≥98%, 5 mg

Chelerythrine chloride, ≥98%, 5 mg

Synonyms 1,2-Dimethoxy-N-methyl-[1,3]-benzodioxolo[5,6c]phenanthridinium

CAS Number: 3895-92-9 Molecular Formula: C21H18NO4Cl Molecular Weight: 383.8

EC Number: 223-444-9 MDL Number: MFCD00060717

Packaging size: 5 mg

SKU 0215888805
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Description

Product Description

Chelerythrine is a benzophenanthridine alkaloid.

Application Notes

Chelerythrine Chloride has been shown to inhibit protein kinase C (PKC) by interaction with the PKC catalytic domain. It has also been shown to inhibit PKC translocation from the cytosol to the membrane in isolated ileal synaptosomes.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Inhibits protein kinase C (PKC) by interaction with the PKC catalytic domain | Inhibits PKC translocation from the cytosol to the membrane in isolated ileal synaptosomes

Specifications
SKU 0215888805
Alternate Names 1,2-Dimethoxy-N-methyl-[1,3]-benzodioxolo[5,6c]phenanthridinium
Application Notes Chelerythrine Chloride has been shown to inhibit protein kinase C (PKC) by interaction with the PKC catalytic domain. It has also been shown to inhibit PKC translocation from the cytosol to the membrane in isolated ileal synaptosomes.
Base Catalog Number 15888805
Biochemical Physiological Actions Chelerythrine affects translocation of PKC from cytosol to plasma membrane. Shown to prevent neurite growth. Induces apoptosis in a concentration and schedule-dependent manner.
CAS # 3895-92-9
EC Number 223-444-9
Hazard Statements H302-H312-H315-H319-H332-H335
Melting Point 206 - 208 °C(Lit.)
Molecular Formula C21H18NO4Cl
Molecular Weight 383.8
Pack Size 5 mg
Purity ≥98%
RTECS Number FL9200000
Safety Symbol GHS07
Solubility Soluble in water (2 mg/mL), methanol (5 mg/mL - clear yellowish solution) and DMSO (4 mg/mL).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.