Cathepsin G,≥95%, 2 - 4 μg/mg protein

Cathepsin G,≥95%, 2 - 4 μg/mg protein

Synonyms E.C. 3.4.21.20

CAS Number: 107200-92-0

MDL Number: MFCD00130750

SKU 02191344-CF
Inquire
Request a quote
Description

Product Description

Cathepsin G

Application Notes

Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Enzymes | Inhibitors | Substrates

Specifications
SKU 02191344-CF
Alternate Names E.C. 3.4.21.20
Application Notes Cathepsin G act as a bacteriocidal reagent. Catrhepsin G is often referred to as a chymotrypsin-like enzyme, since it preferentially cleaves proteins on the carboxyl side of leucine, methionine, and phenylalanine. Cathepsin G can be assayed with substrates such as azocasein, Suc-Ala-Ala-Pro-Phe-NPhNO2, and MeOSUC-Ala-Ala-Pro-Met-NPh-NO2. Cathepsin G also has a specificity of action on the oxidized B chain of insulin and on BSA, which indicates a closer similarity to porcine chymotrypsin C than to bovine chymotrypsin A.
Base Catalog Number 191344
Biochemical Physiological Actions Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
CAS # 107200-92-0
Format Powder
Purity ≥95%
Source Human Neutrophils
Specific Activity 2 - 4 μ/mg protein
Unit Definition The amount of enzyme that hydrolyzes one µmole of Suc-ala-ala-pro-phe-pNA (1mM) per minute 25 °C in pH 7.5, with 1.6 M NaCl.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.