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Ethylenediaminetetraacetic acid, disodium salt, dihydrate, cell culture reagent, ≥99%, 100 g

Ethylenediaminetetraacetic acid, disodium salt, dihydrate, cell culture reagent, ≥99%, 100 g

CN¥0.00

SKU: 0219465980

Synonyms
EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid
CAS Number:
60-00-4
Molecular Formula:
C10H16N2O8
Molecular Weight:
292.3
Beilstein Registry Number:
1716295
EC Number:
200-449-4
MDL Number:
MFCD00003541
Packaging size:
100 g
Product Description

Ethylenediamine Tetraacetic Acid is a polyamino carboxylic acid hexadentate ligand.

Application Notes

Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chelating agent

Specifications
SKU 0219465980
Alternate Names EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid
Application Notes Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
Auto Ignition > 200 °C (DIN 51794) (Lit.)
Base Catalog Number 19465980
Beilstein Registry Number 1716295
CAS # 60-00-4
Density ca. 860 kg/m<sup>3</sup> (bulk density) (Lit.)
EC Number 200-449-4
Flash Point > 100 °C (closed cup and DIN 51758) (Lit.)
Grade Cell Culture Grade
Hazard Statements H319
Melting Point 250 °C (dec.), 236 - 246 °C (Lit.)
Molecular Formula C10H16N2O8
Molecular Weight 292.3
Pack Size 100 g
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pH 2 - 3 (saturated solution)
pKa 2.0, 2.7, 6.2, 10.3 (Lit.)
Purity ≥99%
RTECS Number AH4025000
Safety Symbol GHS07
Solubility Soluble in 3M NaOH (160 mg/mL); 1 M aq soln: Clear, Colorless & Complete, No Black Specks, Haze Free.
Typical Working Concentration EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 mM.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)