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Tetramisole hydrochloride, 10 g

Tetramisole hydrochloride, 10 g

CN¥0.00

SKU: 0215211910

Synonyms
DL-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-b]-thiazole hydrochloride; (±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
CAS Number:
5086-74-8
Molecular Formula:
C11H12N2S*HCl
Molecular Weight:
240.76
Beilstein Registry Number:
4358989
EC Number:
225-799-5
MDL Number:
MFCD00005536
Packaging size:
10 g
Product Description

Tetramisole is an alkaline phosphatase inhibitor. It is a racemic mixture of (+) and (-) isomers. The (-) isomer (levamisole) accounts for most of the biological activity of tetramisole.

Application Notes

Suitable for inhibition of various mammalian alkaline phosphatases (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited. Structure-activity relationship for tetramisole derivatives as alkaline phosphatase inhibitors. In addition to its use in enzyme and protein phosphorylation studies, tetramisole has been used to study membrane, tissue and animal systems.Tetramisole is an antihelminthic agent used in veterinary applications to treat helminth or worm infections.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used in enzyme and protein phosphorylation studies

Specifications
SKU 0215211910
Alternate Names DL-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-b]-thiazole hydrochloride; (±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
Application Notes Suitable for inhibition of various mammalian alkaline phosphatases (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited. Structure-activity relationship for tetramisole derivatives as alkaline phosphatase inhibitors. In addition to its use in enzyme and protein phosphorylation studies, tetramisole has been used to study membrane, tissue and animal systems.Tetramisole is an antihelminthic agent used in veterinary applications to treat helminth or worm infections.
Base Catalog Number 15211910
Beilstein Registry Number 4358989
CAS # 5086-74-8
EC Number 225-799-5
Hazard Statements H302-H315-H319-H335
Melting Point 266 - 267 °C (Lit.)
Molecular Formula C11H12N2S*HCl
Molecular Weight 240.76
Pack Size 10 g
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
pKa 8.0 (Lit.)
RTECS Number NJ5950000
Safety Symbol GHS07
Solubility Soluble in water (50 mg/mL - clear colorless soltion).
Typical Working Concentration Tetramisole has been used to inhibit alkaline phosphatase in the effective range of 0.4 – 2 mM.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.