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Prostaglandin E2, γ-irradiated, ≥99%

Prostaglandin E2, γ-irradiated, ≥99%

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Key features and details

Prostaglandin E2

SKU: 02195461-CF

Synonyms
5Z,11α,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Dinoprostone; PGE2
CAS Number:
363-24-6
Molecular Formula:
C20H32O5
Molecular Weight:
352.471 g/mol
Beilstein Registry Number:
4709356
EC Number:
206-656-6
MDL Number:
MFCD00077861
Product Description

Prostaglandin E2

Application Notes

Prostaglandin E2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Induces cervical ripening and parturition

Specifications
SKU 02195461-CF
Alternate Names 5Z,11α,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Dinoprostone; PGE2
Application Notes Prostaglandin E2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation.
Base Catalog Number 195461
Beilstein Registry Number 4709356
Biochemical Physiological Actions Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
CAS # 363-24-6
EC Number 206-656-6
Format Powder
Hazard Statements H302-H360
Melting Point 67 °C
Molecular Formula C20H32O5
Molecular Weight 352.471 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
Purity ≥99%
RTECS Number UK8000000
Safety Symbol GHS07, GHS08
Solubility Water Solubility58.1 mg/L
Source Synthetic
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificates of Analysis

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