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Staurosporine, molecular biology reagent, ≥98%

Staurosporine, molecular biology reagent, ≥98%

Key features and details

Staurosporine

SKU: 02194805-CF

Synonyms
Antibiotic AM-2282
CAS Number:
62996-74-1
Molecular Formula:
C28H26N4O3
Molecular Weight:
466.541 g/mol
Beilstein Registry Number:
1060573
MDL Number:
MFCD00077402
Product Description

Staurosporine

Application Notes

Staurosporine from Streptomyces sp. was used to induce cell death in MDCK, 293T, Vero, HeLa, and Swiss Webster primary macrophage cells. It was used to study the effect of caspase activation on human sperm quality.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02194805-CF
Alternate Names Antibiotic AM-2282
Application Notes Staurosporine from Streptomyces sp. was used to induce cell death in MDCK, 293T, Vero, HeLa, and Swiss Webster primary macrophage cells. It was used to study the effect of caspase activation on human sperm quality.
Base Catalog Number 194805
Beilstein Registry Number 1060573
Biochemical Physiological Actions Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.Partially reverses MDR, sensitizing cells with MDR phenotype to cytotoxic agents. Inhibits Pgp phosphorylation. However, functional significance of Pgp phosphorylation is ill defined.
CAS # 62996-74-1
Format Film
Grade Molecular Biology Grade
Hazard Statements H340-H350
Molecular Formula C28H26N4O3
Molecular Weight 466.541 g/mol
Personal Protective Equipment Eyeshields, full-face particle respirator , Gloves, respirator cartridge, respirator filter
Purity ≥98%
Safety Symbol GHS08
Source Streptomyces sp.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)

Material Safety Data Sheet

Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United States)