Catalase occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.It promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.Defects in catalase are the cause of acatalasemia,a metabolic disorder characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
|Alternate Names||H2O2:H2O2 oxidoreductase|
|Base Catalog Number||191341|
|Biochemical Physiological Actions||Catalase activates the decomposition of hydrogen peroxide, a reactive oxygen species, into water and oxygen. It functions as a natural antioxidant, protecting cells against oxidative damage to proteins, lipids and nucleic acids. Catalase has also been used to study the role reactive oxygen species play in gene expression and apoptosis.|
|Format||20mM NaCl, pH 7.0 composed of four identical subunits. Negative for HBsAg and HIV antibodies., Supplied as frozen solution of 1mg/mL in 1.5mM sodium phosphate|
|Personal Protective Equipment||Eyeshields, Gloves, respirator filter|
|Unit Definition||One unit is defined as the amount of enzyme that will decompose 1 μmole of H2O2 per minute at 25 °C, pH 7.0.|
|Usage Statement||Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.|