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Retinol (all trans)

Retinol (all trans)

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Key features and details

Retinol(All Trans)

SKU: 02190268-CF

Synonyms
Vitamin A alcohol; Axerophthol; Vitamin A; Vitamin A1; all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; Anti-Infective Vitamin
CAS Number:
68-26-8
Molecular Formula:
C20H30O
Molecular Weight:
286.459 g/mol
Beilstein Registry Number:
403040
EC Number:
200-683-7
MDL Number:
MFCD00001552
Product Description

Retinol(All Trans)

Application Notes

Retinol is an effective antioxidant displaying lipoperoxy radical scavenging activity. The interactions between Retinol and Vitamin E (α-tocopherol) in suppressing lipid peroxidation were observed in bovine retinal membrane preparations. It may influence the production of transition vesicles by stimulating the activity of a protein disulfide isomeraselike activity involved in vesicle formation. Retinol (10 µM) stimulated DNA synthesis and possibly repair mechanisms in Sertoli cells of rat.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antioxidant | Treatment of acute promyelocytic leukemia

Specifications
SKU 02190268-CF
Alternate Names Vitamin A alcohol; Axerophthol; Vitamin A; Vitamin A1; all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; Anti-Infective Vitamin
Application Notes Retinol is an effective antioxidant displaying lipoperoxy radical scavenging activity. The interactions between Retinol and Vitamin E (α-tocopherol) in suppressing lipid peroxidation were observed in bovine retinal membrane preparations. It may influence the production of transition vesicles by stimulating the activity of a protein disulfide isomeraselike activity involved in vesicle formation. Retinol (10 µM) stimulated DNA synthesis and possibly repair mechanisms in Sertoli cells of rat.
Base Catalog Number 190268
Beilstein Registry Number 403040
Biochemical Physiological Actions Ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.
Boiling Point 279 to 280° F at 1e-06 mm Hg (NTP, 1992)
CAS # 68-26-8
EC Number 200-683-7
Extinction Coefficient EM(325nm) = 52,480 (ethanol); E1%(324-325nm) = 1835 (ethanol)(Lit.)
Format Powder
Hazard Statements H302-H315
Melting Point 144 to 147° F (NTP, 1992)
Molecular Formula C20H30O
Molecular Weight 286.459 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
RTECS Number VH6750000
Safety Symbol GHS07
Solubility Practically insoluble (NTP, 1992)
Source Synthetic
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 7.5X10-8 mm Hg at 25 deg C /Estimated/
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