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Ampicillin, trihydrate

Ampicillin, trihydrate

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Key features and details

Ampicillin Trihydrate

SKU: 02190147-CF

Synonyms
Aminobenzylpenicillin trihydrate; alpha-Aminobenzylpenicillin trihydrate ;D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid
CAS Number:
7177-48-2
Molecular Formula:
C16H19N3O4S·3H2O
Molecular Weight:
403.45 g/mol
Beilstein Registry Number:
5399534
EC Number:
200-709-7
MDL Number:
MFCD00072036
Product Description

Ampicillin Trihydrate

Application Notes

Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02190147-CF
Alternate Names Aminobenzylpenicillin trihydrate; alpha-Aminobenzylpenicillin trihydrate ;D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid
Application Notes Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.
Base Catalog Number 190147
Beilstein Registry Number 5399534
Biochemical Physiological Actions A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS # 7177-48-2
EC Number 200-709-7
Format Powder
Hazard Statements H315-H317-H319-H334-H335
Melting Point 388 to 392° F (decomposes) (NTP, 1992)
Molecular Formula C16H19N3O4S·3H2O
Molecular Weight 403.45 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
pKa At 25 °C ,pKa = 2.5 (-COOH),pKa = 7.3 (-NH2) (Lit.)
RTECS Number XH8425000
Safety Symbol GHS07, GHS08
Solubility 1 to 10 mg/mL at 70° F (NTP, 1992)
Sterilization of Solutions Autoclaving solutions of ampicillin will destroy activity. Solutions can be sterilized by filtration (0.22 um filter) and stored frozen (-20 °C or below). Frozen solutions can be stored for up to 3 months.
Typical Working Concentration 100 mg/liter for both gram positive and gram negative bacteria. It is typically stable in media at 37 °C for approximately 3 days.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

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