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β-Nicotinamide adenine dinucleotide reduced, disodium salt, ≥98%

β-Nicotinamide adenine dinucleotide reduced, disodium salt, ≥98%

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Key features and details

β-Nicotinamide Adenine Dinucleotide Reduced Disodium Salt

SKU: 02160050-CF

Synonyms
β-NADH, 2Na; Reduced DPN; Cozymase, reduced form; Dihydrophosphopyridine nucleotide; Dihydronicotinamide adenine dinucleotide; Diphosphopyridine nucleotide, reduced form; β-DPNH; DPNH; NADH
CAS Number:
24292-60-2
Molecular Formula:
C21H27N7O14P2Na2
Molecular Weight:
787.372 g/mol
EC Number:
210-123-3
MDL Number:
MFCD03791273
Product Description

β-Nicotinamide Adenine Dinucleotide Reduced Disodium Salt

Application Notes

β-Nicotinamide adenine dinucleotide and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Oxidation reduction reactions

Specifications
SKU 02160050-CF
Alternate Names β-NADH, 2Na; Reduced DPN; Cozymase, reduced form; Dihydrophosphopyridine nucleotide; Dihydronicotinamide adenine dinucleotide; Diphosphopyridine nucleotide, reduced form; β-DPNH; DPNH; NADH
Application Notes β-Nicotinamide adenine dinucleotide and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
Base Catalog Number 160050
Biochemical Physiological Actions NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, beta-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD+/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.
CAS # 24292-60-2
EC Number 210-123-3
Extinction Coefficient EmM= 6.22 (340 nm) and 14.4 (259 nm, pH 9.5)(Lit.)
Format Powder
Hazard Statements H315-H319-H335
Molecular Formula C21H27N7O14P2Na2
Molecular Weight 787.372 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Purity ≥98%
Safety Symbol GHS07
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (water): 258 - 260 nm
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