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Thiamphenicol

Thiamphenicol

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Key features and details

Thiamphenicol

SKU: 02156846-CF

Synonyms
D -threo-2,2-dichloro-N-[ β-hydroxy-α-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide
CAS Number:
15318-45-3
Molecular Formula:
C12H15Cl2NO5S
Molecular Weight:
356.214 g/mol
Beilstein Registry Number:
2819542
EC Number:
239-355-3
MDL Number:
MFCD00467983
Product Description

Thiamphenicol

Application Notes

Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibacterial | Antibiotics

Specifications
SKU 02156846-CF
Alternate Names D -threo-2,2-dichloro-N-[ β-hydroxy-α-(hydroxymethyl)-p-(methyl- sulfonyl)phenethyl]-acetamide
Application Notes Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Base Catalog Number 156846
Beilstein Registry Number 2819542
Biochemical Physiological Actions Thiamphenicol inhibits mitochondrial protein synthesis of proteins such as cytochrome c oxidase.
CAS # 15318-45-3
EC Number 239-355-3
Molecular Formula C12H15Cl2NO5S
Molecular Weight 356.214 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
RTECS Number AB6680000
Solubility >53.4 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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