Cart
 
In Stock

Novobiocin, sodium salt

Novobiocin, sodium salt

CN¥0.00

Key features and details

Novobiocin Sodium Salt

SKU: 02155957-CF

Synonyms
Albamycin; Cathomycin sodium
CAS Number:
1476-53-5
Molecular Formula:
C31H35N2O11Na
Molecular Weight:
634.614 g/mol
EC Number:
216-023-6
Product Description

Novobiocin Sodium Salt

Application Notes

For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.Novobiocin is used to study heat shock protein inhibition and to produce positively supercoiled plasmid DNA.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02155957-CF
Alternate Names Albamycin; Cathomycin sodium
Application Notes For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.Novobiocin is used to study heat shock protein inhibition and to produce positively supercoiled plasmid DNA.
Base Catalog Number 155957
Biochemical Physiological Actions Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II.Antimicrobial spectrum: Gram-positive bacterial.Novobiocin inhibits DNA synthesis by inhibiting bacterial DNA gyrase targeting the GyrB subunit of the enzyme involved in energy transduction. Novobiocin acts as a competitive inhibitors of the ATPase reaction catalysed by GyrB 2. It is also a Hsp90 inhibitor 3. Antimicrobial spectrum: Gram-positive bacterial.
CAS # 1476-53-5
EC Number 216-023-6
Extinction Coefficient E1%= 600 (0.1 M NAOH)
Format Powder
Molecular Formula C31H35N2O11Na
Molecular Weight 634.614 g/mol
Optical Rotation -38.0°(2.5 g/100 ml ethanol at24°C for the free acid)
Potency ~900 µg/mg
RTECS Number RD5425000
Typical Working Concentration The minimum inhibitory concentration (MIC) toward gram-positive bacteria is 0.1 to 4 µg/ml
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λmax: 307 nm
Citations
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)

Material Safety Data Sheet

Material Safety Data Sheet
English (Emirates)
Material Safety Data Sheet
French (Switzerland)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
German (Switzerland)
Material Safety Data Sheet
Swedish (Sweden)
Material Safety Data Sheet
Portuguese (Portugal)
Material Safety Data Sheet
Spanish (Spain)
Material Safety Data Sheet
Norvegian (Norway)
Material Safety Data Sheet
Spanish (Mexico)
Material Safety Data Sheet
English (Malta)
Material Safety Data Sheet
German (Luxembourg)
Material Safety Data Sheet
Japanese (Japan)
Material Safety Data Sheet
English (Ireland)
Material Safety Data Sheet
Indonesian (Indonesia)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (India)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United Kingdom)
Material Safety Data Sheet
German (Germany)
Material Safety Data Sheet
French (France)
Material Safety Data Sheet
Finnish (Finland)
Material Safety Data Sheet
English (United Kingdom)
Material Safety Data Sheet
French (Canada)
Material Safety Data Sheet
English (Canada)
Material Safety Data Sheet
French (Belgium)
Material Safety Data Sheet
English (Australia)
Material Safety Data Sheet
German (Austria)
Material Safety Data Sheet
Chinese (China)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (Emirates)
Material Safety Data Sheet
German (Austria)
Material Safety Data Sheet
English (Australia)
Material Safety Data Sheet
French (Belgium)
Material Safety Data Sheet
Dutch (Belgium)
Material Safety Data Sheet
English (Canada)
Material Safety Data Sheet
French (Canada)
Material Safety Data Sheet
German (Switzerland)
Material Safety Data Sheet
French (Switzerland)
Material Safety Data Sheet
Italian (Switzerland)
Material Safety Data Sheet
English Chinese (China)
Material Safety Data Sheet
German (Germany)
Material Safety Data Sheet
Spanish (Spain)
Material Safety Data Sheet
English (United Kingdom)
Material Safety Data Sheet
Finnish (Finland)
Material Safety Data Sheet
French (France)
Material Safety Data Sheet
English (United Kingdom)
Material Safety Data Sheet
Tawanese (Hong-Kong)
Material Safety Data Sheet
Indonesian (Indonesia)
Material Safety Data Sheet
English (Ireland)
Material Safety Data Sheet
English (India)
Material Safety Data Sheet
Italian (Italy)
Material Safety Data Sheet
Japanese (Japan)
Material Safety Data Sheet
Korean (South Korea)
Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
German (Luxembourg)
Material Safety Data Sheet
English (Malta)
Material Safety Data Sheet
Spanish (Mexico)
Material Safety Data Sheet
Dutch (Netherlands)
Material Safety Data Sheet
Norvegian (Norway)
Material Safety Data Sheet
Portuguese (Portugal)
Material Safety Data Sheet
Russian (Russia)
Material Safety Data Sheet
Swedish (Sweden)
Material Safety Data Sheet
Tawanese (Taiwan)
Material Safety Data Sheet
English (United States)