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Antipain hydrochloride

Antipain hydrochloride

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Key features and details

Antipain Hydrochloride

SKU: 02152843-CF

Synonyms
L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde
CAS Number:
37682-72-7
Molecular Formula:
C27H44N10O6 (free acid)
Molecular Weight:
677.629 g/mol
EC Number:
253-631-0
Product Description

Antipain Hydrochloride

Application Notes

Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Reversible inhibitor of serine/cysteine proteases

Specifications
SKU 02152843-CF
Alternate Names L-Valinamide; [(S)-1-Carboxy-2-phenylethyl]- carbamoyl-Arg-Val-Arg-al; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-arginyl-L-valyl-argininal; [(S)-1-Carboxy-phenethyl]-carbamoyl-Arg-Val-Arg-aldehyde
Application Notes Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.
Base Catalog Number 152843
Biochemical Physiological Actions Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.
CAS # 37682-72-7
EC Number 253-631-0
Format Powder
Hazard Statements H302
Molecular Formula C27H44N10O6 (free acid)
Molecular Weight 677.629 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
RTECS Number YV9350700
Safety Symbol GHS07
Typical Working Concentration Effective concentration is 1 to 100 µM.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
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