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D-Penicillamine, ≥99%

D-Penicillamine, ≥99%

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Key features and details

D-Penicillamine

SKU: 02151805-CF

Synonyms
3,3-Dimethyl-D-cysteine; 3-Mercapto-D-valine; D-(-)-2-Amino-3-mercapto-3-methylbutanoic acid
CAS Number:
52-67-5
Molecular Formula:
C5H11NO2S
Molecular Weight:
149.208 g/mol
Beilstein Registry Number:
1722375
EC Number:
200-148-8
MDL Number:
MFCD00064302
Product Description

D-Penicillamine

Application Notes

It is used as an antirheumatic and as a chelating agent in Wilson's disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02151805-CF
Alternate Names 3,3-Dimethyl-D-cysteine; 3-Mercapto-D-valine; D-(-)-2-Amino-3-mercapto-3-methylbutanoic acid
Application Notes It is used as an antirheumatic and as a chelating agent in Wilson's disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes.
Base Catalog Number 151805
Beilstein Registry Number 1722375
Biochemical Physiological Actions Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity.
CAS # 52-67-5
EC Number 200-148-8
Format Powder
Hazard Statements H315-H319-H335
Melting Point 198.5 °C
Molecular Formula C5H11NO2S
Molecular Weight 149.208 g/mol
Personal Protective Equipment dust mask, Eyeshields, Gloves
Purity ≥99%
RTECS Number YV9425000
Safety Symbol GHS07
Solubility Water Solubility111000 mg/L (at 20 °C)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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