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Amikacin, phytopure™

Amikacin, phytopure™

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Key features and details

CAS Number: 35717-28-5

SKU: 02150342-CF

Synonyms
1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A; O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; Lukadin
CAS Number:
37517-28-5
Molecular Formula:
C22H43N5O13
Molecular Weight:
585.60
Beilstein Registry Number:
1445422
EC Number:
253-538-5
MDL Number:
MFCD11045969
Product Description

From Kanamycin A. An amino-glycoside antibiotic that works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. It is effective against gram-negative bacteria, fungi and mycobacteria.

Application Notes

Amikacin is most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02150342-CF
Alternate Names 1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A; O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; Lukadin
Application Notes Amikacin is most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter.
Base Catalog Number 150342
Beilstein Registry Number 1445422
Biochemical Physiological Actions Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading. It interferes with the translocation of tRNA from the A-site to the P-site.
CAS # 37517-28-5
EC Number 253-538-5
Melting Point 203-204 °C
Molecular Formula C22H43N5O13
Molecular Weight 585.60
Optical Rotation +100.5°
Personal Protective Equipment Eyeshields, Gloves,respirator filter
Potency ~900 µg/mg
RTECS Number WK1955000
Solubility Water Solubility185000 mg/L (at 25 °C)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 5.79X10-28 mm Hg at 25 deg C (est)
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