α-Tocopherol is a powerful inhibitor of the proliferation of estrogen receptor positive and estrogen receptor negative human breast cancer cell lines in a dose dependent manner in vitro.
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|Alternate Names||Vitamin E Acetate, all-rac-α-Tocopheryl acetate|
|Application Notes||α-Tocopherol is a powerful inhibitor of the proliferation of estrogen receptor positive and estrogen receptor negative human breast cancer cell lines in a dose dependent manner in vitro.|
|Base Catalog Number||100555|
|Beilstein Registry Number||97512|
|Biochemical Physiological Actions||Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.|
|Boiling Point||363Â° F at 0.01 mm Hg (NTP, 1992)|
|Density||0.9507 at 78.1Â° F (NTP, 1992)|
|Melting Point||82Â° F (NTP, 1992)|
|Molecular Weight||472.754 g/mol|
|Personal Protective Equipment||Eyeshields, Gloves|
|Preparation Method||Cut with corn starch and hydrolyzed protein.|
|Solubility||less than 1 mg/mL at 63Â° F (NTP, 1992)|
|Specific Activity||250 u/g|