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Rifampin, 150 mg

Rifampin, 150 mg

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Key features and details

Rifampin

SKU: 0219479581

Synonyms
Rifamycin AMP; Rifampicin; 3-(4-Methylpiperazinyliminomethyl)rifamycin SV; Rifampicin;
CAS Number:
13294-46-1
Molecular Formula:
C43H58N4O12
Beilstein Registry Number:
5723476
EC Number:
236-312-0
MDL Number:
MFCD00151389
Packaging size:
150 mg
Product Description

Rifampin

Application Notes

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic | Inhibitor of transcription initiation | Antipruritic agent

Specifications
SKU 0219479581
Alternate Names Rifamycin AMP; Rifampicin; 3-(4-Methylpiperazinyliminomethyl)rifamycin SV; Rifampicin;
Application Notes Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.
Base Catalog Number 19479581
Beilstein Registry Number 5723476
Biochemical Physiological Actions Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. It Inhibits the assembly of DNA and protein into mature virus particles.
CAS # 13294-46-1
EC Number 236-312-0
Extinction Coefficient EmM (max absorbance, phosphate buffer,pH 7.38): 33.20 (237 nm); 32.10 (255 nm); 27.00 (334 nm);15.40 (475 nm)(Lit.)
Format Powder
Grade Molecular Biology Grade
Hazard Statements H302-H315-H319-H335
Isoelectric Point 4.8(in water)(Lit.)
Molecular Formula C43H58N4O12
Optical Rotation [α]D25°=+10.6° (c=0.5% in CDCl3)(Lit.)
Pack Size 150 mg
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pKa pKa (in water):1.7 (4-hydroxyl group), 7.9 (4-piperazine nitrogen); in methylcellosolve-water (4:1): 3.6 (4-hydroxyl group), 6.7 (3-piperazine nitrogen)(Lit.)
RTECS Number VJ7000000
Safety Symbol GHS07
Sterility γ-Irradiated
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max, methanol: 237 - 239 nm
Citations
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)