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Okadaic acid, sodium salt, 100 μg

Okadaic acid, sodium salt, 100 μg

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Key features and details

Okadaic Acid Sodium Salt

SKU: 0215897480

Synonyms
OA; 9,10-deepithio-9,10-didehydroacanthifolicin
CAS Number:
78111-17-8
Molecular Formula:
C44H67O13Na
Molecular Weight:
805.015 g/mol
MDL Number:
MFCD00210208
Packaging size:
100 μg
Product Description

Okadaic Acid Sodium Salt

Application Notes

Okadaic acid has been used to study various cellular processes such as the cell cycle and apoptosis including microtubule organization and tau hosphorylation. This phosphatase inhibitor has also played a role in the study of nitric oxide metabolism and calcium signaling. In addition, okadaic acid has been shown to activate transcription of the Cox-2 gene, disrupt golgi, arrest transport in the rough endoplasmic reticulum, and affect neurotransmitter release.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Inhibitor of type 1 and 2A protein phosphatases | Tumor promotor

Specifications
SKU 0215897480
Alternate Names OA; 9,10-deepithio-9,10-didehydroacanthifolicin
Application Notes Okadaic acid has been used to study various cellular processes such as the cell cycle and apoptosis including microtubule organization and tau hosphorylation. This phosphatase inhibitor has also played a role in the study of nitric oxide metabolism and calcium signaling. In addition, okadaic acid has been shown to activate transcription of the Cox-2 gene, disrupt golgi, arrest transport in the rough endoplasmic reticulum, and affect neurotransmitter release.
Base Catalog Number 15897480
Biochemical Physiological Actions Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases.
CAS # 78111-17-8
Hazard Statements H301-H311-H315-H331
Melting Point 171-175 deg C; 164-166 deg C
Molecular Formula C44H67O13Na
Molecular Weight 805.015 g/mol
Pack Size 100 μg
Preparation Method Preparation: Isolated from cultured Prorocentrum concavum by preparative flash, medium pressure and high performance liquid chromatography. Salf form generated in aqueous sodium hydroxide methanol solution.
Purity ≥98%
RTECS Number AA8227800
Safety Symbol GHS06
Solubility Readily soluble in many organic solvents, degrading in acid or base.
Source Prorocentrum concavum
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Datasheet

Datasheet