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Feline anti-globulin (Coombs' Test) reagent, 2 mL

Feline anti-globulin (Coombs' Test) reagent, 2 mL

CN¥0.00

Key features and details

The anti-globulin or Coombs' test is widely used to detect the presence of antibody in the diagnosis of autoimmune hemolytic anemia.

SKU: 08646381

Packaging size:
2 mL
Product Description

The anti-globulin or Coombs' test is widely used to detect the presence of antibody in the diagnosis of autoimmune hemolytic anemia. Antibody alone or in the presence of complement injures the cell membrane permitting leakage of RBC material, allowing recognition by the reticuloendothelial cells, thereby leading to phagocytosis and destruction of RBC's. Anti-globulin reagent (Coombs' serum) is prepared by immunizing rabbits with canine IgG, IgM and C3 purified from normal

Application Notes

Feline anti-globulin reagent (Coombs') has been widely used for the diagnosis of autoimmune hemolytic anemia (AIHA) in a variety of species. Several disease entities resembling AIHA and immune-mediated hemolytic anemia have been recognized in the cat. Feline antiglobulin test can be used as a test to aid the diagnosis of AIHA and immune-mediated hemolytic anemia in the cat.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Immunoassays | Autoimmune Hemolytic Anemia (AIHA) diagnosis

Specifications
SKU 08646381
Antibody Type Polyclonal Antibody
Application Notes Feline anti-globulin reagent (Coombs') has been widely used for the diagnosis of autoimmune hemolytic anemia (AIHA) in a variety of species. Several disease entities resembling AIHA and immune-mediated hemolytic anemia have been recognized in the cat. Feline antiglobulin test can be used as a test to aid the diagnosis of AIHA and immune-mediated hemolytic anemia in the cat.
Base Catalog Number 646381
Conjugate Unconjugated
Disease Screened Autoimmune hemolytic anemia (AIHA)
Formulation Details Lyophilized
Host Rabbit
Pack Size 2 mL
Preparation Method Antibodies are produced in rabbits by immunization with feline immunoglobulins and formulated with selected beta globulins including the C3 component of complement. The resulting antiserum is heated at 56°C for 30 minutes to inactivate rabbit complement. Heteroagglutinins are absorbed with pooled normal feline red blood cells. The reagent is tested with normal and antibody-coated feline red blood cells to assure its specificity.
Solubility Soluble in water
Species Reactivity Cat
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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