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Blasticidin S hydrochloride, phytopure™

Blasticidin S hydrochloride, phytopure™

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CAS Number: 9041-93-4

SKU: 02150477-CF

Synonyms
BLA-S; Cytovirin; Blasticidine S hydrochloride; 4-[[3-Amino-5-[(aminoiminomethyl)-1-oxopentyl]amino]-1-(4-amino-2-oxo- 1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-b-D-erythro-hex-2-enopyranuronic acid
CAS Number:
3513-03-9
Molecular Formula:
C17H26N8O5 - HCl
Molecular Weight:
458.90
MDL Number:
MFCD02091640
Product Description

Broad spectrum nucleoside antibiotic. Inhibits protein synthesis in prokaryotic and eukaryotic organisms. Suitable for selection of cells carrying plasmids conferring blasticidin resistance.

Application Notes

Blasticidin S is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. Blasticidiin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells. It is also used to study protein synthesis at the level of peptide bond formation.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antimicrobial

Specifications
SKU 02150477-CF
Alternate Names BLA-S; Cytovirin; Blasticidine S hydrochloride; 4-[[3-Amino-5-[(aminoiminomethyl)-1-oxopentyl]amino]-1-(4-amino-2-oxo- 1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-b-D-erythro-hex-2-enopyranuronic acid
Application Notes Blasticidin S is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. Blasticidiin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells. It is also used to study protein synthesis at the level of peptide bond formation.
Base Catalog Number 150477
Biochemical Physiological Actions Blasticidin S inhibits hydrolysis of peptidyl-tRNA induced by release factors. It enhances the binding of tRNA to the large subunit of ribosomes and to an extent inhibits peptide bond formation.
CAS # 3513-03-9
Hazard Statements H300
Molecular Formula C17H26N8O5 - HCl
Molecular Weight 458.90
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator , Gloves, respirator filter, respirator cartridges
RTECS Number EC4900000
Safety Symbol GHS06
Source Streptomyces griseochromogenes
Typical Working Concentration Typically used at 2 - 10 µg/mL for mammalian cell selection.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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