Ampicillin

Ampicillin

Synonyms D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid

CAS Number: 69-53-4 Molecular Formula: C16H19N3O4S Molecular Weight: 349.405 g/mol

Beilstein Registry Number: 1090925 EC Number: 200-709-7 MDL Number: MFCD00005175

SKU 02190146-CF
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Description

Product Description

Ampicillin

Application Notes

Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibacterial | Antibiotics

Specifications
SKU 02190146-CF
Alternate Names D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid
Application Notes Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid.
Base Catalog Number 190146
Beilstein Registry Number 1090925
Biochemical Physiological Actions Ampicillin is a β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
CAS # 69-53-4
EC Number 200-709-7
Format White powder
Grade Anhydrous
Hazard Statements H315-H317-H319-H334-H335
Melting Point 388 to 392° F (decomposes) (NTP, 1992)
Molecular Formula C16H19N3O4S
Molecular Weight 349.405 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
pKa pKa = 2.5 (-COOH) pKa = 7.3 (-NH2) at 25 °C
RTECS Number XH8350000
Safety Symbol GHS07, GHS08
Solubility 1 to 10 mg/mL at 70° F (NTP, 1992)
Typical Working Concentration 100 mg/liter for both gram positive and gram negative bacteria
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.