乙醛脱氢酶

乙醛脱氢酶

Synonyms Aldehyde:NAD[P]+ oxidoreductase; ALDH

CAS Number: 9028-86-0

EC Number: 232-845-3 MDL Number: MFCD00081306

SKU 02190679-CF
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Description

Product Description

Aldehyde Dehydrogenase

Application Notes

Aldehyde dehydrogenase oxidizes a number of aliphatic and aromatic aldehydes. Acetyl-GSH is not hydrolyzed.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Acting on aldehydes or oxo groups

Specifications
SKU 02190679-CF
Alternate Names Aldehyde:NAD[P]+ oxidoreductase; ALDH
Application Notes Aldehyde dehydrogenase oxidizes a number of aliphatic and aromatic aldehydes. Acetyl-GSH is not hydrolyzed.
Base Catalog Number 190679
Biochemical Physiological Actions Aldehyde dehydrogenase is a tetramer and has several different isoforms. The enzyme tested in 0.01 M pyrophosphate buffer shows a sharp optimum around pH 9.3 with acetaldehyde as substrate. Potassium ions and cysteine are essential for the enzyme's activity. Rubidium or NH4+ can be substituted for K+, and glutathione for cysteine. Lithium, Na+, and Cs+ inhibit the reaction. Aldehyde dehydrogenase is inhibited by propylurea, crotonaldehyde, n-propyl isocyanate, cyclohexyl isocyanate, 1-n-propyl-1-[(4-chlorophenyl)sulphonyl]-3-n-propylurea, and 1-methyl-1-[(4-chlorophenyl)sulphonyl]-3-n-propylurea. The enzyme may be utilized to quantitate aldehydes present in blood.
CAS # 9028-86-0
EC Number 232-845-3
Extinction Coefficient 9.4 (279 nm)(Lit)
Format Freeze dried stabilized powder, Potassium Activated
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Source Yeast
Specific Activity Protein-~5 u/mg, solid-≥1 u/mg solid
Unit Definition One unit causes the oxidation of one µ mole of acetaldehyde to acetic acid per minute at pH 8.0 and 25 °C in the presence of potassium ions and thiols.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.