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腺苷,9-β-D-呋喃核糖基腺嘌呤

腺苷,9-β-D-呋喃核糖基腺嘌呤

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CAS:58-61-7 腺苷

SKU: 02100199-CF

Synonyms
9- β-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-β-D-ribofuranoside
CAS Number:
58-61-7
Molecular Formula:
C10H13N5O4
Molecular Weight:
267.245 g/mol
Beilstein Registry Number:
93029
EC Number:
200-389-9
MDL Number:
MFCD00005752
Product Description

Adenosine

Application Notes

Adenosine is active in cardiovascular disorders. It is indicated in cases of angina pectoris on account of its property of increasing the coronary output and in cases of hypertension on account of its vasodilator action. It is also active on the peripheral circulation, dilating the capillary vessels. It has also been recommended in the treatment of agranulocytosis. It induces apoptosis in human leukemia HL-60 cells and also has anti-arrhythmic properties.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Treatment of cardiovascular disorders and agranulocytosis

Specifications
SKU 02100199-CF
Alternate Names 9- β-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-β-D-ribofuranoside
Application Notes Adenosine is active in cardiovascular disorders. It is indicated in cases of angina pectoris on account of its property of increasing the coronary output and in cases of hypertension on account of its vasodilator action. It is also active on the peripheral circulation, dilating the capillary vessels. It has also been recommended in the treatment of agranulocytosis. It induces apoptosis in human leukemia HL-60 cells and also has anti-arrhythmic properties.
Base Catalog Number 100199
Beilstein Registry Number 93029
Biochemical Physiological Actions Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD).
CAS # 58-61-7
EC Number 200-389-9
Extinction Coefficient 15.4 (259 nm in 0.01 M PO4, pH 7)
Format Powder, Free Base
Hazard Statements H302-H313
Melting Point 500 to 518° F (NTP, 1992)
Molecular Formula C10H13N5O4
Molecular Weight 267.245 g/mol
Optical Rotation α20/D -70 °, c = 2 in 5% NaOH (lit.)
Personal Protective Equipment Eyeshields, Gloves, respirator filter
pH pH = 4.5-7.5 (solution of 3 mg/mL adenosine and 9 mg/mL <a class="pubchem-internal-link CID-5234" href="https://pubchem.ncbi.nlm.nih.gov/compound/sodium%20chloride">sodium chloride</a> in <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>)
Purity ≥98%
Refractive Index n20D 1.91 (Lit.)
RTECS Number AU7175000
Solubility >40.1 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λmax (1N HCl)-255 - 260 nm OD250/OD260 - 0.80 - 0.90 OD280/OD260 - 0.17 - 0.24
Vapor Pressure 6.0X10-15 mm Hg at 25 deg C (est)
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