6-Aminonicotinamide, 1 g

6-Aminonicotinamide, 1 g

Synonyms 6-Aminopyridine-3-carboxamide

CAS Number: 329-89-5 Molecular Formula: C6H7N3O Molecular Weight: 137.14

Beilstein Registry Number: 116042 EC Number: 206-349-7 MDL Number: MFCD00006327

Packaging size: 1 g

SKU 0215010301
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Specifications
SKU 0215010301
Alternate Names 6-Aminopyridine-3-carboxamide
Application Notes 6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.
Base Catalog Number 15010301
Beilstein Registry Number 116042
Biochemical Physiological Actions 6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM). 6-AN also reduces cardiovascular oxidative injury following ischemia/reperfusion. In addition, 6-AN causes glial neurodegeneration.
CAS # 329-89-5
EC Number 206-349-7
Hazard Statements H360
Melting Point 240 - 250 °C
Molecular Formula C6H7N3O
Molecular Weight 137.14
Pack Size 1 g
Personal Protective Equipment Eyeshields, Gloves, respirator cartridges
RTECS Number US4550000
Safety Symbol GHS08
Solubility Soluble in warm methanol (0.2/20).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.