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FastMitophagy™ detection kit, 1 kit

FastMitophagy™ detection kit, 1 kit

CN¥0.00

Key features and details

The FastMitophagy Detection Kit is specifically designed for mitophagy detection in mammalian cells.

SKU: 092690201

Packaging size:
1 Kit
Product Description

The FastMitophagy Detection Kit is specifically designed for mitophagy detection in mammalian cells. Mitophagy is the selective degradation of defective mitochondria by autophagy following DNA damage or oxidative stress. It serves as a specific elimination system by sequestering dysfunctional mitochondria into autophagosomes, fusing the phagosome to lysosomes, and degrading them by digestion. Since its first observation in 1962, mitophagy has attracted intense research for cell homeostasis and development in mammalian cells. Recent research efforts are directed towards further elucidating the role of induced autophagy as a cell survival response to stress, microbial infection, and disease (e.g., cancer, Alzheimer's disease, and Parkinson's disease).
This kit is composed of a mitophagy dye, a reagent for detection of mitophagy, and lysosome dye (Lyso dye). Mitophagy dye initially accumulates in intact mitochondria and becomes immobilized via chemical bonding, resulting in a very weak fluorescence due to the influence of the surrounding environment. When mitophagy is induced, the damaged mitochondria fuses to lysosome and the Mitophagy dye emits a high fluorescence. Lyso dye is used to confirm the fusion of Mitophagy dye - labeled mitochondria and lysosome.
Each kit contains 5 µg of Mitophagy Dye and 30 µg Lyso Dye which is enough for 5 x 96 well plates or 25 assays when using a 35 mm.
Benefits of using FastMitophagy Detection Kit:

  • Simple procedure: just add the Mitophagy dye - no need for transfection
  • More sensitive than other autophagy markers

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 092690201
Base Catalog Number 2690201
Format Kit
Pack Size 1 Kit
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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Manuals
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Material Safety Data Sheet

Material Safety Data Sheet
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Material Safety Data Sheet
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Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United Kingdom)
Material Safety Data Sheet
English (United States)

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