Ethylene glycol-bis-(Β-amino-ethylether)-N,N,N′,N′-tetraacetic acid

Ethylene glycol-bis-(Β-amino-ethylether)-N,N,N′,N′-tetraacetic acid

Synonyms EGTA; GEDTA; O,O'-bis(2-aminoethyl)ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid

CAS Number: 67-42-5 Molecular Formula: C14H24N2O10 Molecular Weight: 380.35 g/mol

Beilstein Registry Number: 1717370 EC Number: 200-651-2 MDL Number: MFCD00004291

SKU 02194823-CF
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Description

Product Description

Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid

Application Notes

Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chelating agent

Specifications
SKU 02194823-CF
Alternate Names EGTA; GEDTA; O,O'-bis(2-aminoethyl)ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid
Application Notes Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.
Base Catalog Number 194823
Beilstein Registry Number 1717370
CAS # 67-42-5
EC Number 200-651-2
Format Powder
Grade Molecular Biology Grade
Molecular Formula C14H24N2O10
Molecular Weight 380.35 g/mol
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pKa < 2, 2.7, 8.8, and 9.5 (Lit.)
Purity ≥97%
RTECS Number AH3760000
Typical Working Concentration as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.