CAFFEINE UN1544-III

CAFFEINE UN1544-III

Synonyms 1,3,7-Trimethylxanthine; 1,3,7-Trimethyl-2,6-dioxopurine (monohydrate); Methyltheobromine

CAS Number: 58-08-2 Molecular Formula: C8H10N4O2*H2O Molecular Weight: 212.2

Beilstein Registry Number: 17705 EC Number: 200-362-1 MDL Number: MFCD00005758

Packaging size: 100 g

SKU 0210119480
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Specifications
SKU 0210119480
Alternate Names 1,3,7-Trimethylxanthine; 1,3,7-Trimethyl-2,6-dioxopurine (monohydrate); Methyltheobromine
Application Notes Caffeine Monohydrate protects against virus induction and chemical carcinogenesis. commonly used as a mild stimulant. It overrides the cell cycle effects of various chemicals such as protease inhibitors, thereby preventing apoptosis and it has been shown to inhibit cellular DNA repair mechanisms.
Beilstein Registry Number 17705
Biochemical Physiological Actions A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
Chemical Class Pharmaceuticals
Density 1.23 g/mL(Lit.)
Detection Method FTIR
EC Number 200-362-1
Hazard Statements H302
Applications Protects against virus induction and chemical carcinogenesis
MDL # MFCD00005758
Melting Point 230 - 240 °C
Moisture Content 4 - 8%
Molecular Formula C<sub>8</sub>H<sub>10</sub>N<sub>4</sub>O<sub>2</sub>*H<sub>2</sub>O
Molecular Weight 212.2
Pack Size 100 g
Personal Protective Equipment Dust mask, Eyeshields, Gloves, Facesheilds
pH 6 - 7.5(1% aq soln)
Physical Appearance White Powder
pKa 14.0 at 25 °C(Lit.)
Related Products 02150114
Risk Phrases R:22
RTECS Number EV6475000
Safety Symbol GHS07
Solubility Soluble in hot water.
Storage and Handling Store at Room Temperature(15-30 °C).
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance λmax (water) 271 - 273 nm