CHAPSO, ≥98%
SKU: 02190320-CF
CHAPSO is the hydroxy analog of CHAPS; a nondenaturing zwitterionic detergent for solubilizing proteins, especially integral membrane proteins while maintaining the functional capability of the protein of interest. It has a more polar head group than CHAPS, giving it a greater solubility. CHAPSO has a high CMC (8 mM) and does not denature membrane-bound proteins. It can solubilize the opiate receptor in a state exhibiting reversible binding of opiates.
Application Notes
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Solubilization of integral membrane proteins
| SKU | 02190320-CF |
| Aggregation Number | 11 |
| Alternate Names | 3-[(3-Cholamidopropyl)-dimethylammonio]-2-hydroxy-1-propane sulfonate |
| Application Notes | A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins. |
| Base Catalog Number | 190320 |
| Beilstein Registry Number | 5842642 |
| CAS # | 82473-24-3 |
| Critical Micelle Concentration | 8 mM |
| Hazard Statements | H315-H319-H335 |
| Melting Point | 184-186 °C (Lit.) |
| Molecular Formula | C32H58N2O8S |
| Molecular Weight | 630.9 |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| pH | 5.0 - 9.0 (10% aq soln) |
| Purity | ≥98% |
| Safety Symbol | GHS07 |
| Solubility | Soluble in water (100 mg/mL - clear, colorless to slight yellowish solution), methanol (40 mg/mL- clear, colorless solution). |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | OD350 nm (1%aq soln): <0.04 |