Product Description
MP Biomedicals CD63 Rabbit Monoclonal Antibody offers high specificity and potency and consistency against human/mouse/rat CD63 (a classical exosome biomarker involved in cancer cells metastasis), which has been experimentally validated in WB and IHC assays.
Usage Statement
Research use only, not for direct human use.
Specifications
| SKU | 08L100021 |
| Alternate Names | CD63; LAMP-3; ME491; MLA1; OMA81H; TSPAN30; CD63 antigen; CD63 |
| Antibody Type | Monoclonal Antibody |
| Background_information | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also, this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
| Bioreactivity | High specificity against CD63 antigen has been experimentally validated. |
| Concentration | Please check the vial’s label |
| Conjugate | Unconjugated |
| Formulation Details | In PBS buffer with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3-7.4. This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. This antibody is stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
| Grade | Molecular Grade |
| Host | Rabbit |
| Immunogen | With the full-length human CD63 protein as an immunogen |
| Isotype | Rabbit IgG |
| Molecular Weight | Observed at 30-50 kDa |
| Pack Size | 100 µL |
| Preparation Method | Affinity purification |
| Solubility | Dissolves in Tris or PBS buffer immediately |
| Species Reactivity | Human, Mouse, Rat |
| Storage | -20° |
| Typical Working Concentration | WB: 1:500 to 1:2,000; IHC: 1:50 to 1:200. |
| Uniprot Number | P08962 |
| Usage Statement | Research use only, not for direct human use. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
English (United States)
Safety Data Sheets
English (United States)
Brochures
Brochures
English (United States)
Brochures
English (United States)
Brochures
English (United States)