5-Azacytidine

Name: 5-Azacytidine
SKU: 02100821-CF

A$0.00

Key features and details

5-Azacytidine

SKU: 02100821-CF

Synonyms

4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 5-Azacitidine; Ladakamycin

CAS Number:

320-67-2

Molecular Formula:

C8H12N4O5

Molecular Weight:

244.207 g/mol

Beilstein Registry Number:

620461

EC Number:

206-280-2

MDL Number:

MFCD00006539

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Product Description

5-Azacytidine

Application Notes

5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Inhibition of protein synthesis | bacteriostatic | antitumor | mutagenic agent

Specifications

SKU	02100821-CF
Alternate Names	4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 5-Azacitidine; Ladakamycin
Application Notes	5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.
Base Catalog Number	100821
Beilstein Registry Number	620461
Biochemical Physiological Actions	A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes
CAS #	320-67-2
EC Number	206-280-2
Format	Powder
Hazard Statements	H302-H350
Melting Point	442 to 446° F (decomposes) (NTP, 1992)
Molecular Formula	C8H12N4O5
Molecular Weight	244.207 g/mol
Personal Protective Equipment	Eyeshields, full-face particle respirator , Gloves, respirator cartridge, respirator filter
RTECS Number	XZ3017500
Safety Symbol	GHS07, GHS08
Solubility	>36.6 [ug/mL]
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.